a1

It may soon be too late to end the global monkeypox epidemic.

“We are losing the window to be able to contain this outbreak,” Boghuma Titanji, an infectious diseases doctor and virologist at Emory University in Atlanta said July 21 during a seminar sponsored by the Harvard Kennedy School’s Belfer Center for Science and International Affairs.

On July 23, Tedros Adhanom Ghebreyesus, director of the World Health Organization declared the global outbreak of monkeypox is a public health emergency of international concern, the organization’s highest state of alert. The WHO committee evaluating the matter was split on whether the outbreak constitutes an international emergency, but Ghebreyesus decided that enough conditions were met to warrant the designation.
Monkeypox has infected more than 15,700 people since the beginning of May, according to Global.health (SN: 5/26/22). More than 2,800 cases have been reported in the United States as of July 22, the U.S. Centers for Disease Control and Prevention report.

“Although I am declaring a public health emergency of international concern, for the moment this is an outbreak that is concentrated among men who have sex with men, especially those with multiple sexual partners,” Ghebreyesus said in a statement. “That means that this is an outbreak that can be stopped with the right strategies in the right groups.”

Monkeypox has caused outbreaks for decades in some parts of Africa, Anne Rimoin, an epidemiologist at the UCLA Fielding School of Public Health, said at the Harvard seminar. But the virus “has been neglected by the global health community.” Monkeypox “has been giving us warning signals” for years in Congo, Nigeria and other parts of West Africa, but has only gotten attention once it recently started causing cases outside of the continent, Rimoin said.

There has been no concerted global effort to contain the virus, which is related to smallpox, Titanji said. Each country has been left to set its own policies.

That has led to disparities. Well-resourced countries have had at least some access to testing, vaccines and medications, which may help limit the spread of the virus or the severity of the disease. Resource-poor nations often lack that access, leaving them with limited ability to track or control the virus. Continued spread of monkeypox in resource-poor countries could leave places that do manage to contain an initial outbreak vulnerable to reintroductions, Jay K. Varma, director of the Cornell Center for Pandemic Prevention and Response in New York City, said in the seminar. The WHO emergency declaration may lead to a more concerted international effort that could make more resources available to contain the spread of the virus.

Even for the wealthiest countries, containing the outbreak is a challenge. Questions abound about how the virus is transmitted, and whether vaccines and treatments — when people can get them — can halt its spread. Even diagnosing the disease can be tricky, with testing often hard to come by and missed diagnoses potentially leading to more cases.

The vast majority of monkeypox cases in the global outbreak have been among men who have sex with men. Of 528 people infected with monkeypox in 16 countries, 98 percent identified as gay or bisexual men, researchers report July 21 in the New England Journal of Medicine.

In some countries with outbreaks, “gay men are criminalized,” Kai Kupferschmidt, a correspondent for Science magazine, said during the seminar. In those countries, “people cannot access good information to help them keep from getting infected and cannot access health care if they do get infected. In these countries, it becomes really difficult to even see the problem,” he said.

Ghebreyesus urged all countries to “work closely with communities of men who have sex with men, to design and deliver effective information and services, and to adopt measures that protect the health, human rights and dignity of affected communities. Stigma and discrimination can be as dangerous as any virus,” he said in a statement.

Doctors might also miss cases of monkeypox because of the unusual presentation of the illness in this outbreak, compared with earlier outbreaks. For instance, in the NEJM study, only a quarter of patients had monkeypox lesions on their faces and only 10 percent had the sores on their palms or soles of their feet. Those body parts have been among some of the most affected in other outbreaks.

Instead, 73 percent of people in the study had lesions in the anal and genital regions and 55 percent on the trunk, arms or legs. Some people also had lesions in their mouths and throats. Most of the people in the study had fewer than 10 lesions, with 54 people having only a single lesion on their genitals, making confusion with herpes or syphilis possible, even easy.

Seventy people in the study were admitted to the hospital. Of those, 21 were hospitalized because of pain, mostly severe rectal pain. Others had eye lesions, kidney damage, inflammation of the heart or throat swelling that prevented them from taking in liquids.

Those complications fit with what health officials across the United States have been seeing. “While mortality appears very low, which is great, morbidity has been much higher than any of us expected,” Mary Foote, the medical director of the New York City Department of Health and Mental Hygiene, said July 14 in a news briefing sponsored by the Infectious Diseases Society of America.

“A lot of people with this infection are really suffering, and some may be at risk of permanent damage and scarring. We see many people with symptoms so severe that they are unable to go to the bathroom, urinate or eat without excruciating pain,” Foote said.

A small number of women and children have also gotten monkeypox in the outbreak. Two children in the United States have been diagnosed with monkeypox, CDC director Rochelle Walensky said July 22 in an interview with the Washington Post. Both children were social contacts of men that have sex with men, she said.

A child in the Netherlands who had no contact with anyone known to be infected with the virus also got monkeypox, researchers report July 21 in Eurosurveillance. His case raises the possibility that monkeypox may be spreading undetected more broadly in communities than realized.

“I don’t think it’s surprising that we are occasionally going to see cases in individuals who are not gay, bisexual or other men who have sex with men. The social networks we have as humans mean we have contact with a lot of different people,” Jennifer McQuiston, deputy director of the CDC’s Division of High Consequence Pathogens and Pathology said July 22 during a White House news briefing.

Exactly how the child in the Netherlands became infected is a matter of speculation. Monkeypox typically spreads among people through close contact with infected people or with clothing, bedding or towels used by people with the disease. Examination of viral DNA showed that the boy isn’t connected to any of the known cases in the Netherlands. He traveled to Turkey in June and may have gotten infected there or while traveling.

The boy has very low levels of IgA antibodies, which patrol mucous membranes and help prevent infections there. Low levels of the antibodies could make him vulnerable to respiratory infections. People can get infected with monkeypox through droplets given off by infected people during close face-to-face interactions, such as close conversation, kissing or during medical exams. But patterns of infection clearly indicate that monkeypox isn’t airborne the way COVID-19 or other respiratory viruses are, Kupferschmidt said.

Details of how monkeypox spreads are still unknown. For instance, researchers don’t know whether the virus can be transmitted through semen as a sexually transmitted disease. Researchers have found evidence of viral DNA in semen, saliva, urine and feces, but that may just be inactive remnants of the virus. So far, no researchers have reported finding infectious virus in genital body fluids that might be exchanged during sex. Also unknown is whether getting infected through mucous membranes during sexual contact would shield against catching the virus later, Rimoin said.

Scientists are questioning whether the monkeypox virus has changed or whether it has simply found a niche social-sexual network among gay and bisexual men that may enable the virus to spread more efficiently, Titanji said. It may be that there are different transmission patterns in historically affected countries and newly affected countries that require different strategies to stop the spread, she said.

Researchers also need to do good studies to figure out how well vaccines and therapeutics work and under what circumstances, Rimoin said. WHO’s emergency declaration includes recommendations for increasing testing and surveillance and for seeding up research on vaccines, treatments and other virus containment measures.

One thing is clear, Rimoin said. “We’re giving this virus room to run like it never has before.” People have passed the buck, leaving others to work out the problem of monkeypox, she said. But now, “it’s everybody’s problem to solve.”

Dinosaurs might have been endothermic, or warm-blooded…. The combination of large size, endothermy and naked skin may explain the extinction of dinosaurs. About 65 million years ago there was a sharp drop in temperature…. Dinosaurs, lacking skin insulation and too large to burrow underground … could not survive. Meanwhile, evidence has come that … the shells [of their eggs] became progressively thinner … too fragile to support the growing embryo.

Update
Some dinosaurs may have been warm-blooded and some could have laid soft-shelled eggs (SN: 7/12/14, p. 6). But neither trait led to the reptiles’ demise. In the late 1970s, geologists proposed that an asteroid strike triggered a mass extinction (1/25/92, p. 56), killing more than 75 percent of life on Earth. That theory is now widely accepted. Scientists have even found the killer’s calling card: a crater about 180 kilometers wide on the coast of the Yucatán Peninsula in Mexico. The asteroid probably crash landed there in the springtime 66 million years ago, fossils hint (SN: 3/26/22, p. 8).

A century from now, when biologists are playing games of clones and engineers are playing games of drones, physicists will still pledge their loyalty to the Kingdoms of Substance and Force.

Physicists know the subjects of these kingdoms as fermions and bosons. Fermions are the fundamental particles of matter; bosons transmit forces that govern the behavior of the matter particles. The math describing these particles and their relationships forms the “standard model” of particle physics. Or as Nobel laureate Frank Wilczek calls it, “The Core Theory.”
Wilczek’s core theory differs from the usual notion of standard model. His core includes gravity, as described by Einstein’s general theory of relativity. General relativity is an exquisite theory of gravity, but it doesn’t fit in with the math for the standard model’s three forces (the strong and weak nuclear forces and electromagnetism). But maybe someday it will. Perhaps even by 100 years from now.

At least, that’s among the many predictions that Wilczek has made for the century ahead. In a recent paper titled “Physics in 100 Years,” he offers a forecast for future discoveries and inventions that science writers of the future will be salivating over. (The paper is based on a talk celebrating the 250th anniversary of Brown University. He was asked to make predictions for 250 years from now, but regarded 100 as more reasonable.)

Wilczek does not claim that his forecast will be accurate. He considers it more an exercise in imagination, anchored in thorough knowledge of today’s major questions and the latest advances in scientific techniques and capabilities. Where those two factors meet, Wilczek sees the potential for premonition. His ruminations result in a vision of the future suitable for a trilogy or two of science fiction films. They would involve the unification of the kingdoms of physics and a more intimate relationship between them and the human mind.

Among Wilczek’s prognostications is the discovery of supersymmetric particles, heavyweight partners to the matter and force particles of the Core Theory. Such partner particles would reveal a deep symmetry underlying matter and force, thereby combining the kingdoms and further promoting the idea of unification as a key path to truth about nature. Wilczek also foresees the discovery of proton decay, even though exhaustive searches for it have so far failed to find it. If protons disintegrate (after, on average, trillions upon trillions of years), matter as we know it has a limited lease on life. On the other hand, lack of finding proton decay has been a barrier to figuring out a theory that successfully unifies the math for all of nature’s particles and forces. And Wilczek predicts that:

The unification of gravity with the other forces will become more intimate, and have observable consequences.

He also anticipates that gravity waves will be observed and used to probe the physics of the distant (and early) universe; that the laws of physics, rather than emphasizing energy, will someday be rewritten in terms of “information and its transformations”; and that “biological memory, cognitive processing, motivation, and emotion will be understood at the molecular level.”

And all that’s just the beginning. He then assesses the implications of future advances in computing. Part of the coming computation revolution, he foresees, will focus on its use for doing science:

Calculation will increasingly replace experimentation in design of useful materials, catalysts, and drugs, leading to much greater efficiency and new opportunities for creativity.

Advanced calculational power will also be applied to understanding the atomic nucleus more precisely, conferring the ability…

to manipulate atomic nuclei dexterously … enabling (for example) ultradense energy storage and ultrahigh energy lasers.

Even more dramatically, computing power will be employed to enhance itself:

Capable three-dimensional, fault-tolerant, self-repairing computers will be developed.… Self-assembling, self-reproducing, and autonomously creative machines will be developed.

And those achievements will imply that:

Bootstrap engineering projects wherein machines, starting from crude raw materials, and with minimal human supervision, build other sophisticated machines (notably including titanic computers) will be underway.

Ultimately, such sophisticated computing machines will enable artificial intelligence that would even impress Harold Finch on Person of Interest (which is probably Edward Snowden’s favorite TV show).

Imagine, for instance, the ways that superpowerful computing could enhance the human senses. Aided by electronic prosthetics, people could experience the full continuous range of colors in the visible part of the electromagnetic spectrum, not just those accessible to the tricolor-sensitive human eye. Perhaps the beauty that physicists and mathematicians “see” in their equations can be transformed into works of art beamed directly into the brain.

Artificial intelligence endowed with such power would enable many other futuristic fantasies. As Wilczek notes, the “life of mind” could be altered in strange new ways. For one thing, computationally precise knowledge of a state of mind would permit new possibilities for manipulating it. “An entity capable of accurately recording its state could purposefully enter loops, to re-live especially enjoyable episodes,” Wilczek points out.

And if all that doesn’t sound weird enough, we haven’t even invoked quantum mechanics yet. Wilczek forecasts that large-scale quantum computers will be realized, in turn leading to “quantum artificial intelligence.”

“A quantum mind could experience a superposition of ‘mutually contradictory’ states, or allow different parts of its wave function to explore vastly different scenarios in parallel,” Wilczek points out. “Being based on reversible computation, such a mind could revisit the past at will, and could be equipped to superpose past and present.”

And with quantum artificial intelligence at its disposal, the human mind’s sensory tentacles will not merely be enhanced but also dispersed. With quantum communication, humans can be linked by quantum messaging to sensory devices at vast distances from their bodies. “An immersive experience of ‘being there’ will not necessarily involve being there, physically,” Wilczek writes. “This will be an important element of the expansion of human culture beyond Earth.”

In other words, it will be a web of intelligence, rather than a network of physical settlements, that will expand human culture throughout the cosmos. Such “expanded identities” will be able to comprehend the kingdoms of substance and force on their own quantum terms, as the mind itself merges with space and time.

Wilczek’s visions imply a future existence in which nature is viewed from a vastly different perspective, conditioned by a radical reorientation of the human mind to its world. And perhaps messing with the mind so drastically should be worrisome. But let’s not forget that the century gone by has also messed with the mind and its perspectives in profound ways — with television, for instance, talk radio, the Internet, smartphones and blogs. A little quantum computer mind manipulation is unlikely to make things any worse.

Humans have long tried to wrangle water. We’ve straightened once-meandering rivers for shipping purposes. We’ve constructed levees along rivers and lakes to protect people from flooding. We’ve erected entire cities on drained and filled-in wetlands. We’ve built dams on rivers to hoard water for later use.

“Water seems malleable, cooperative, willing to flow where we direct it,” environmental journalist Erica Gies writes in Water Always Wins. But it’s not, she argues.

Levees, which narrow channels causing water to flow higher and faster, nearly always break. Cities on former wetlands flood regularly — often catastrophically. Dams starve downstream environs of sediment needed to protect coastal areas against rising seas. Straightened streams flow faster than meandering ones, scouring away riverbed ecosystems and giving water less time to seep downward and replenish groundwater supplies.

In addition to laying out this damage done by supposed water control, Gies takes readers on a hopeful global tour of solutions to these woes. Along the way, she introduces “water detectives”— scientists, engineers, urban planners and many others who, instead of trying to control water, ask: What does water want?
These water detectives have found ways to give the slippery substance the time and space it needs to trickle underground. Around Seattle’s Thornton Creek, for instance, reclaimed land now allows for regular flooding, which has rejuvenated depleted riverbed habitat and created an urban oasis. In California’s Central Valley, scientists want to find ways to shunt unpolluted stormwater into ancient, sediment-filled subsurface canyons that make ideal aquifers. Feeding groundwater supplies will in turn nourish rivers from below, helping to maintain water levels and ecosystems.

While some people are exploring new ways to manage water, others are leaning on ancestral knowledge. Without the use of hydrologic mapping tools, Indigenous peoples of the Andes have a detailed understanding of the plumbing that links surface waters with underground storage. Researchers in Peru are now studying Indigenous methods of water storage, which don’t require dams, in hopes of ensuring a steady flow of water to Lima — Peru’s populous capital that’s periodically afflicted by water scarcity. These studies may help convince those steeped in concrete-centric solutions to try something new. “Decision makers come from a culture of concrete,” Gies writes, in which dams, pipes and desalination plants are standard.

Understanding how to work with, not against, water will help humankind weather this age of drought and deluge that’s being exacerbated by climate change. Controlling water, Gies convincingly argues, is an illusion. Instead, we must learn to live within our water means because water will undoubtedly win.

Biologist Martin Dančák didn’t set out to find a plant species new to science. But on a hike through a rainforest in Borneo, he and colleagues stumbled on a subterranean surprise.

Hidden beneath the soil and inside dark, mossy pockets below tree roots, carnivorous pitcher plants dangled their deathtraps underground. The pitchers can look like hollow eggplants and probably lure unsuspecting prey into their sewer hole-like traps. Once an ant or a beetle steps in, the insect falls to its death, drowning in a stew of digestive juices (SN: 11/22/16). Until now, scientists had never observed pitcher plants with traps almost exclusively entombed in earth.
“We were, of course, astonished as nobody would expect that a pitcher plant with underground traps could exist,” says Dančák, of Palacký University in Olomouc, Czech Republic.

That’s because pitchers tend to be fragile. But the new species’ hidden traps have fleshy walls that may help them push against soil as they grow underground, Dančák and colleagues report June 23 in PhytoKeys. Because the buried pitchers stay concealed from sight, the team named the species Nepenthes pudica, a nod to the Latin word for bashful.

The work “highlights how much biodiversity still exists that we haven’t fully discovered,” says Leonora Bittleston, a biologist at Boise State University in Idaho who was not involved with the study. It’s possible that other pitcher plant species may have traps lurking underground and scientists just haven’t noticed yet, she says. “I think a lot of people don’t really dig down.”

The next generation of dark matter detectors has arrived.

A massive new effort to detect the elusive substance has reported its first results. Following a time-honored tradition of dark matter hunters, the experiment, called LZ, didn’t find dark matter. But it has done that better than ever before, physicists report July 7 in a virtual webinar and a paper posted on LZ’s website. And with several additional years of data-taking planned from LZ and other experiments like it, physicists are hopeful they’ll finally get a glimpse of dark matter.
“Dark matter remains one of the biggest mysteries in particle physics today,” LZ spokesperson Hugh Lippincott, a physicist at the University of California, Santa Barbara said during the webinar.

LZ, or LUX-ZEPLIN, aims to discover the unidentified particles that are thought to make up most of the universe’s matter. Although no one has ever conclusively detected a particle of dark matter, its influence on the universe can be seen in the motions of stars and galaxies, and via other cosmic observations (SN: 7/24/18).

Located about 1.5 kilometers underground at the Sanford Underground Research Facility in Lead, S.D., the detector is filled with 10 metric tons of liquid xenon. If dark matter particles crash into the nuclei of any of those xenon atoms, they would produce flashes of light that the detector would pick up.

The LZ experiment is one of a new generation of bigger, badder dark matter detectors based on liquid xenon, which also includes XENONnT in Gran Sasso National Laboratory in Italy and PandaX-4T in the China Jinping Underground Laboratory. The experiments aim to detect a theorized type of dark matter called Weakly Interacting Massive Particles, or WIMPs (SN: 12/13/16). Scientists scaled up the search to allow for a better chance of spying the particles, with each detector containing multiple tons of liquid xenon.

Using only about 60 days’ worth of data, LZ has already surpassed earlier efforts to pin down WIMPs (SN: 5/28/18). “It’s really impressive what they’ve been able to pull off; it’s a technological marvel,” says theoretical physicist Dan Hooper of Fermilab in Batavia, Ill, who was not involved with the study.

Although LZ’s search came up empty, “the way something’s going to be discovered is when you have multiple years in a row of running,” says LZ collaborator Matthew Szydagis, a physicist at the University at Albany in New York. LZ is expected to run for about five years, and data from that extended period may provide physicists’ best chance to find the particles.

Now that the detector has proven its potential, says LZ physicist Kevin Lesko of Lawrence Berkeley National Laboratory in California, “we’re excited about what we’re going to see.”

Tyrannosaurus rex’s tiny arms have launched a thousand sarcastic memes: I love you this much; can you pass the salt?; row, row, row your … oh.

But back off, snarky jokesters. A newfound species of big-headed carnivorous dinosaur with tiny forelimbs suggests those arms weren’t just an evolutionary punchline. Arm reduction — alongside giant heads — evolved independently in different dinosaur lineages, researchers report July 7 in Current Biology.

Meraxes gigas, named for a dragon in George R. R. Martin’s “A Song of Ice and Fire” book series, lived between 100 million and 90 million years ago in what’s now Argentina, says Juan Canale, a paleontologist with the country’s CONICET research network who is based in Buenos Aires. Despite the resemblance to T. rex, M. gigas wasn’t a tyrannosaur; it was a carcharodontosaur — a member of a distantly related, lesser-known group of predatory theropod dinosaurs. M. gigas went extinct nearly 20 million years before T. rex walked on Earth.
The M. gigas individual described by Canale and colleagues was about 45 years old and weighed more than four metric tons when it died, they estimate. The fossilized specimen is about 11 meters long, and its skull is heavily ornamented with crests and bumps and tiny hornlets, ornamentations that probably helped attract mates.

Why these dinosaurs had such tiny arms is an enduring mystery. They weren’t for hunting: Both T. rex and M. gigas used their massive heads to hunt prey (SN: 10/22/18). The arms may have shrunk so they were out of the way during the frenzy of group feeding on carcasses.

But, Canale says, M. gigas’ arms were surprisingly muscular, suggesting they were more than just an inconvenient limb. One possibility is that the arms helped lift the animal from a reclining to a standing position. Another is that they aided in mating — perhaps showing a mate some love.

Getting a COVID-19 test has become a regular part of many college students’ lives. That ritual may protect not just those students’ classmates and professors but also their municipal bus drivers, neighbors and other members of the local community, a new study suggests.

Counties where colleges and universities did COVID-19 testing saw fewer COVID-19 cases and deaths than ones with schools that did not do any testing in the fall of 2020, researchers report June 23 in PLOS Digital Health. While previous analyses have shown that counties with colleges that brought students back to campus had more COVID-19 cases than those that continued online instruction, this is the first look at the impact of campus testing on those communities on a national scale (SN: 2/23/21).
“It’s tough to think of universities as just silos within cities; it’s just much more permeable than that,” says Brennan Klein, a network scientist at Northeastern University in Boston.

Colleges that tested their students generally did not see significantly lower case counts than schools that didn’t do testing, Klein and his colleagues found. But the communities surrounding these schools did see fewer cases and deaths. That’s because towns with colleges conducting regular testing had a more accurate sense of how much COVID-19 was circulating in their communities, Klein says, which allowed those towns to understand the risk level and put masking policies and other mitigation strategies in place.

The results highlight the crucial role testing can continue to play as students return to campus this fall, says Sam Scarpino, vice president of pathogen surveillance at the Rockefeller Foundation’s Pandemic Prevention Institute in Washington, D.C. Testing “may not be optional in the fall if we want to keep colleges and universities open safely,” he says.
Finding a flight path
As SARS-CoV-2, the virus that causes COVID-19 rapidly spread around the world in the spring of 2020, it had a swift impact on U.S. college students. Most were abruptly sent home from their dorm rooms, lecture halls, study abroad programs and even spring break outings to spend what would be the remainder of the semester online. And with the start of the fall semester just months away, schools were “flying blind” as to how to bring students back to campus safely, Klein says.

That fall, Klein, Scarpino and their collaborators began to put together a potential flight path for schools by collecting data from COVID-19 dashboards created by universities and the counties surrounding those schools to track cases. The researchers classified schools based on whether they had opted for entirely online learning or in-person teaching. They then divided the schools with in-person learning based on whether they did any testing.

It’s not a perfect comparison, Klein says, because this method groups schools that did one round of testing with those that did consistent surveillance testing. But the team’s analyses still generally show how colleges’ pandemic response impacted their local communities.

Overall, counties with colleges saw more cases and deaths than counties without schools. However, testing helped minimize the increase in cases and deaths. During the fall semester, from August to December, counties with colleges that did testing saw on average 14 fewer deaths per 100,000 people than counties with colleges that brought students back with no testing — 56 deaths per 100,000 versus about 70.
The University of Massachusetts Amherst, with nearly 30,000 undergraduate and graduate students in 2020, is one case study of the value of the testing, Klein says. Throughout the fall semester, the school tested students twice a week. That meant that three times as many tests occurred in the city of Amherst than in neighboring cities, he says. For much of the fall and winter, Amherst had fewer COVID-19 cases per 1,000 residents than its neighboring counties and statewide averages.

Once students left for winter break, campus testing stopped – so overall local testing dropped. When students returned for spring semester in February 2021, area cases spiked — possibly driven by students bringing the coronavirus back from their travels and by being exposed to local residents whose cases may have been missed due to the drop in local testing. Students returned “to a town that has more COVID than they realize” Klein says.

Renewed campus testing not only picked up the spike but quickly prompted mitigation strategies. The university moved classes to Zoom and asked students to remain in their rooms, at one point even telling them that they should not go on walks outdoors. By mid-March, the university reduced the spread of cases on campus and the town once again had a lower COVID-19 case rate than its neighbors for the remainder of the semester, the team found.

The value of testing
It’s helpful to know that testing overall helped protect local communities, says David Paltiel, a public health researcher at the Yale School of Public Health who was not involved with the study. Paltiel was one of the first researchers to call for routine testing on college campuses, regardless of whether students had symptoms.

“I believe that testing and masking and all those things probably were really useful, because in the fall of 2020 we didn’t have a vaccine yet,” he says. Quickly identifying cases and isolating affected students, he adds, was key at the time.
But each school is unique, he says, and the benefit of testing probably varied between schools. And today, two and a half years into the pandemic, the cost-benefit calculation is different now that vaccines are widely available and schools are faced with newer variants of SARS-CoV-2. Some of those variants spread so quickly that even testing twice a week may not catch all cases on campus quickly enough to stop their spread, he says.

As colleges and universities prepare for the fall 2022 semester, he would recommend schools consider testing students as they return to campus with less frequent follow-up surveillance testing to “make sure things aren’t spinning crazy out of control.”

Still, the study shows that regular campus testing can benefit the broader community, Scarpino says. In fact, he hopes to capitalize on the interest in testing for COVID-19 to roll out more expansive public health testing for multiple respiratory viruses, including the flu, in places like college campuses. In addition to PCR tests — the kind that involve sticking a swab up your nose — such efforts might also analyze wastewater and air within buildings for pathogens (SN: 05/28/20).

Unchecked coronavirus transmission continues to disrupt lives — in the United States and globally — and new variants will continue to emerge, he says. “We need to be prepared for another surge of SARS-CoV-2 in the fall when the schools reopen, and we’re back in respiratory season.”

We’ve now seen farther, deeper and more clearly into space than ever before.

A stellar birthplace, a nebula surrounding a dying star, a group of closely interacting galaxies, the first spectrum of an exoplanet’s light. These are some of the first images from the James Webb Space Telescope, released in a NASA news briefing on July 12. This quartet of cosmic scenes follows on the heels of the very first image released from the telescope, a vista of thousands of distant galaxies, presented in a White House briefing on July 11.
“First of all, it’s really gorgeous. And it’s teeming with galaxies,” said JWST Operations Scientist Jane Rigby at the July 12 briefing. “That’s been true of every image we’ve taken with Webb. We can’t take [an image of] blank sky. Everywhere we look, there’s galaxies everywhere.”

Going deep
The galaxies captured in the first released image lie behind a cluster of galaxies about 4.6 billion light-years away. The mass from those closer galaxies distorts spacetime in such a way that objects behind the cluster are magnified, giving astronomers a way to peer more than 13 billion years into the early universe.

Even with that celestial assist, other existing telescopes could never see so far. But the James Webb Space Telescope, also known as JWST, is incredibly large — at 6.5 meters across, its mirror is nearly three times as wide as that of the Hubble Space Telescope. It also sees in the infrared wavelengths of light where distant galaxies appear. Those features give it an edge over previous observatories.

“There’s a sharpness and a clarity we’ve never had,” said Rigby, of NASA’s Goddard Space Flight Center in Greenbelt, Md. “You can really zoom in and play around.”
Although that first image represents the deepest view of the cosmos to date, “this is not a record that will stand for very long,” astronomer Klaus Pontoppidan of the Space Telescope Science Institute in Baltimore said in a June 29 news briefing. “Scientists will very quickly beat that record and go even deeper.”

But JWST wasn’t built only to peer deeper and farther back in time than ever before. The cache of first images and data showcases space scenes both near and far, glimpses of single stars and entire galaxies, and even a peek into the chemical composition of a far-off planet’s atmosphere.

“These are pictures just taken over a period of five days. Every five days, we’re getting more data,” European Space Agency science advisor Mark McCaughrean said at the July 12 briefing. (JWST is an international collaboration among NASA, ESA and the Canadian Space Agency.) “It’s a culmination of decades of work, but it’s just the beginning of decades. What we’ve seen today with these images is essentially that we’re ready now.”
Cosmic cliffs
This image shows the “Cosmic Cliffs,” part of the enormous Carina nebula, a region about 7,600 light-years from Earth where many massive stars are being born. Some of the most famous Hubble Space Telescope images feature this nebula in visible light, but JWST shows it in “infrared fireworks,” Pontoppidan says. JWST’s infrared detectors can see through dust, so the nebula appears especially spangled with stars.
“We’re seeing brand new stars that were previously completely hidden from our view,” said NASA Goddard astrophysicist Amber Straughn.

But molecules in the dust itself are glowing too. Energetic winds from baby stars in the top of the image are pushing and sculpting the wall of gas and dust that runs across the middle. “We see examples of bubbles and cavities and jets that are being blown out from newborn stars,” Straughn said. And gas and dust are the raw material for new stars — and new planets.

“It reminds me that our sun and our planets, and ultimately us, were formed out of this same stuff that we see here,” Straughn said. “We humans really are connected to the universe. We’re made out of the same stuff.”
Foamy nebula
The Southern Ring nebula is an expanding cloud of gas that surrounds a dying star about 2,000 light-years from Earth. In previous Hubble images, the nebula looks like an oblong swimming pool with a fuzzy orange deck and a bright diamond, a white dwarf star, in the middle. JWST expands the view far beyond that, showing more tendrils and structures in the gas than previous telescopes could see.
“You see this bubbly, almost foamy appearance,” said JWST astronomer Karl Gordon, of the Space Telescope Science Institute. In the left hand image, which captures near-infrared light from JWST’s NIRCam instrument, the foaminess traces molecular hydrogen that formed as dust expanded away from the center. The center appears blue due to hot ionized gas heated by the leftover core of the star. Rays of light escape the nebula like the sun peeking through patchy clouds.

In the right-hand image, taken by the MIRI mid-infrared camera, the outer rings look blue and trace hydrocarbons forming on the surface of dust grains. The MIRI image also reveals a second star in the nebula’s core.

“We knew this was a binary star, but we didn’t see much of the actual star that produced this nebula,” Gordon said. “Now in MIRI this star glows red.”
A galactic quintet
Stephan’s Quintet is a group of galaxies about 290 million light-years away that was discovered in 1877. Four of the galaxies are engaged in an intimate gravitational dance, with one member of the group passing through the core of the cluster. (The fifth galaxy is actually much closer to Earth and just appears in a similar spot on the sky.) JWST’s images show off more structure within the galaxies than previous observations did, revealing where stars are being born.

“This is a very important image and area to study,” because it shows the sort of interactions that drive the evolution of galaxies, said JWST scientist Giovanna Giardino of the European Space Agency.

In an image from the MIRI instrument alone, the galaxies look like wispy skeletons reaching towards each other. Two galaxies are clearly close to merging. And in the top galaxy, evidence of a supermassive black hole comes to light. Material swirling around the black hole is heated to extremely high temperatures and glows in infrared light as it falls into the black hole.
An exoplanet’s sky
This “image” is clearly different from the others, but it’s no less scientifically exciting. It shows the spectrum of light from the star WASP 96 as it passes through the atmosphere of its gas giant planet, WASP 96b.

“You get a bunch of what looks like bumps and wiggles to some people but it’s actually full of information content,” said NASA exoplanet scientist Knicole Colón. “You’re actually seeing bumps and wiggles that indicate the presence of water vapor in the atmosphere of this exoplanet.”
The planet is about half the mass of Jupiter and orbits its star every 3.4 days. Previously astronomers thought it had no clouds in its sky, but the new data from JWST show signs of clouds and haze. “There is evidence of clouds and hazes because the water features are not quite as large as we predicted,” Colón said.
A long time coming
These first images and data have been a very long time coming. The telescope that would become JWST was first dreamed up in the 1980s, and the planning and construction suffered years of budget issues and delays (SN: 10/6/21).

The telescope finally launched on December 25. It then had to unfold and assemble itself in space, travel to a gravitationally stable spot about 1.5 million kilometers from Earth, align its insectlike primary mirror made of 18 hexagonal segments and calibrate its science instruments (SN: 1/24/22). There were hundreds of possible points of failure in that process, but the telescope unfurled successfully and got to work.

“We are so thrilled that it works because there’s so much at risk,” says JWST senior project scientist John Mather of NASA’s Goddard Space Flight Center. “The world has trusted us to put our billions into this and make it go, and it works. So it’s an immense relief.”
In the months following, the telescope team released teasers of imagery from calibration, which already showed hundreds of distant, never-before-seen galaxies. But the images now being released are the first full-color pictures made from the data scientists will use to start unraveling mysteries of the universe.

“It sees things that I never dreamed were out there,” Mather says.

For the telescope team, the relief in finally seeing the first images was palpable. “It was like, ‘Oh my god, we made it!’” says image processor Alyssa Pagan, also of Space Telescope Science Institute. “It seems impossible. It’s like the impossible happened.”

In light of the expected anticipation surrounding the first batch of images, the imaging team was sworn to secrecy. “I couldn’t even share it with my wife,” says Pontoppidan, leader of the team that produced the first color science images.

“You’re looking at the deepest image of the universe yet, and you’re the only one who’s seen that,” he says, of the first picture released July 11. “It’s profoundly lonely.” Soon, though, the team of scientists, image processors and science writers was seeing something new every day for weeks as the telescope downloaded the first images. “It’s a crazy experience,” Pontoppidan says. “Once in a lifetime.”

For Pagan, the timing is perfect. “It’s a very unifying thing,” she says. “The world is so polarized right now. I think it could use something that’s a little bit more universal and connecting. It’s a good perspective, to be reminded that we’re part of something so much greater and beautiful.”

JWST is just getting started as it now begins its first round of full science operations. “There’s lots more science to be done,” Mather says. “The mysteries of the universe will not come to an end anytime soon.”

As a journalist covering COVID-19, I’ve had a front-row seat to the pandemic. I’ve been overwhelmed with despair over the death and suffering. I’ve been numb, trying to keep up with the deluge of COVID-19 studies. One balm has been the understanding of colleagues who also report on COVID-19.

I found solace too in Virology, microbiologist Joseph Osmundson’s book of 11 wide-ranging essays, in which he writes of the pandemic and calls for “a new rhetoric of care.” Osmundson includes journal entries from the pandemic, and some of his experi­ences are similar to mine. He dreams he’s at a gathering where no one is masked. He too felt the “density” of the pandemic: “Emotionally dense, with loss and struggle and even some­times joy,” he writes. “Scientifically dense, with papers and pre-prints out every day that need reading and some analysis.”

Osmundson doesn’t just focus on the coronavirus. He jumps from other viruses and the immune system to illness and metaphors for illness, to sex and HIV, to archiving history and whose stories get told. Parts of the book feel like an anthology, with quotes from many writers who have weighed in on these topics. Parts are a call to care for everyone, regardless of race, ethnicity, wealth or who one loves.
Overall, Osmundson questions how society thinks about viruses. “Viruses … are not evil, they don’t invade. They just are,” he writes. “The meaning we give a virus affects how we live with it.” When we describe viruses as enemies and illness as a war, it “assumes the necessity of casualties.” He argues instead to focus resources on caring for one another.

Born in the early 1980s, Osmundson, a gay man, is acutely aware of the messages that come with viruses. “Our generation of gay men came after the plague,” he writes. “HIV didn’t just kill bodies. It killed a type of sex as well, a type of pleasure.” But new therapies have saved lives and altered perceptions. Pre-exposure prophylaxis can prevent infection, while treatment can render HIV untransmissible (SN: 11/15/19). These advances changed our relationship with the virus, Osmundson writes. “I used to think that HIV would make it harder to find love and sex. Now we know that HIV-positive and undetectable is safe. It’s sexy.”

But the biomedicine that can change our relationship with viruses has not been wielded equitably, Osmundson observes. He returns throughout the book to our common humanity. “That fact of all our bodies, vulnerable together, necessitates mutual care.”